Ayurvedic Amalaki Rasayana promotes improved stress tolerance and thus has anti-aging effects in Drosophila melanogaster
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چکیده
منابع مشابه
Ayurvedic Amalaki Rasayana and Rasa-Sindoor suppress neurodegeneration in fly models of Huntington’s and Alzheimer’s diseases
We examined two Ayurvedic Rasayana formulations, claimed to facilitate ‘healthy ageing’, for their role in neuroprotection in fly models of polyQ (127Q and Huntington’s) and Alzheimer’s disorders. Our earlier findings showed that dietary supplement of Amalaki Rasayana, a preparation derived from Indian gooseberry fruits, and Rasa-Sindoor, an organo-metallic Bhasma prepared from mercury and sulp...
متن کاملIn Vivo Effects Of Traditional Ayurvedic Formulations in Drosophila melanogaster Model Relate with Therapeutic Applications
BACKGROUND Ayurveda represents the traditional medicine system of India. Since mechanistic details of therapy in terms of current biology are not available in Ayurvedic literature, modern scientific studies are necessary to understand its major concepts and procedures. It is necessary to examine effects of the whole Ayurvedic formulations rather than their "active" components as is done in most...
متن کاملP01.11. Amalaki Rasayana, an Ayurvedic preparation: to evaluate its effect against experimental gastric ulcers in albino rats
Methods Amalaki Rasayana samples were tested for their antiulcer effect in Charles Foster’s strain albino rats and divided into 4 groups: Control and Ordinary Amalaki Rasayana (O.A.R.), Freeze Dried Amalaki Rasayana (F.D. A.R.), Freeze Dried Amalaki Churna (F.D.A.C.) (100mg/ kg body weight, 7 consecutive days). Gastric ulcer was induced by oral administration of aspirin (400 mg/kg) and with lig...
متن کاملAntimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster.
It is well appreciated that reactive oxygen species (ROS) are deleterious to mammals, including humans, especially when generated in abnormally large quantities from cellular metabolism. Whereas the mechanisms leading to the production of ROS are rather well delineated, the mechanisms underlying tissue susceptibility or tolerance to oxidant stress remain elusive. Through an experimental selecti...
متن کاملInfluence of Amalaki Rasayana on telomerase activity and telomere length in human blood mononuclear cells
BACKGROUND Indian traditional medicine practices use defined rasayana preparations to improve the quality of life in aged individuals. Amalaki Rasayana is one such rasayana prepared from the fruits of Phyllanthus emblica and is popularly used to prevent or treat various age related health conditions. Telomerase activity in the cells maintains telomere length and is implicated in ageing and vari...
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ژورنال
عنوان ژورنال: Journal of Biosciences
سال: 2016
ISSN: 0250-5991,0973-7138
DOI: 10.1007/s12038-016-9641-x